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Factors and Mechanisms for Pharmacokinetic Differences between Pediatric Population and Adults

Many physiologic differences between children and adults may result in age-related changes in pharmacokinetics and pharmacodynamics. Factors such as gastric pH and emptying time, intestinal transit time, immaturity of secretion and activity of bile and pancreatic fluid among other factors determine...

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Detalles Bibliográficos
Autores principales: Fernandez, Eva, Perez, Raul, Hernandez, Alfredo, Tejada, Pilar, Arteta, Marta, Ramos, Jose T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857037/
https://www.ncbi.nlm.nih.gov/pubmed/24310425
http://dx.doi.org/10.3390/pharmaceutics3010053