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Factors and Mechanisms for Pharmacokinetic Differences between Pediatric Population and Adults
Many physiologic differences between children and adults may result in age-related changes in pharmacokinetics and pharmacodynamics. Factors such as gastric pH and emptying time, intestinal transit time, immaturity of secretion and activity of bile and pancreatic fluid among other factors determine...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857037/ https://www.ncbi.nlm.nih.gov/pubmed/24310425 http://dx.doi.org/10.3390/pharmaceutics3010053 |