Role of P-Glycoprotein Expression and Function in Cystinotic Renal Proximal Tubular Cells

P-glycoprotein (P-gp) is an ATP-dependent transporter localized at the apical membrane of the kidney proximal tubules, which plays a role in the efflux of cationic and amphipathic endogenous waste products and xenobiotics, such as drugs, into urine. Studies in mice deficient in P-gp showed generaliz...

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Detalles Bibliográficos
Autores principales: Peeters, Karen, Wilmer, Martijn J., Schoeber, Joost P., Reijnders, Dorien, van den Heuvel, Lambertus P., Masereeuw, Rosalinde, Levtchenko, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857058/
https://www.ncbi.nlm.nih.gov/pubmed/24309308
http://dx.doi.org/10.3390/pharmaceutics3040782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857058/
https://www.ncbi.nlm.nih.gov/pubmed/24309308
http://dx.doi.org/10.3390/pharmaceutics3040782

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