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Adenovirus Vector-Derived VA-RNA-Mediated Innate Immune Responses
The major limitation of the clinical use of replication-incompetent adenovirus (Ad) vectors is the interference by innate immune responses, including induction of inflammatory cytokines and interferons (IFN), following in vivo application of Ad vectors. Ad vector-induced production of inflammatory c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857070/ https://www.ncbi.nlm.nih.gov/pubmed/24310584 http://dx.doi.org/10.3390/pharmaceutics3030338 |