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Adenovirus Vector-Derived VA-RNA-Mediated Innate Immune Responses

The major limitation of the clinical use of replication-incompetent adenovirus (Ad) vectors is the interference by innate immune responses, including induction of inflammatory cytokines and interferons (IFN), following in vivo application of Ad vectors. Ad vector-induced production of inflammatory c...

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Detalles Bibliográficos
Autores principales:	Machitani, Mitsuhiro, Yamaguchi, Tomoko, Shimizu, Kahori, Sakurai, Fuminori, Katayama, Kazufumi, Kawabata, Kenji, Mizuguchi, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2011
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857070/ https://www.ncbi.nlm.nih.gov/pubmed/24310584 http://dx.doi.org/10.3390/pharmaceutics3030338

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