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p53 E3 ubiquitin protein ligase homolog regulates p53 in vivo in the adult mouse eye lens

PURPOSE: p53 is a transcription factor that plays an important role in preventing cancer development. p53 participates in relevant aspects of cell biology, including apoptosis and cell cycle control and must be strictly regulated to maintain normal tissue homeostasis. p53 E3 ubiquitin protein ligase...

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Detalles Bibliográficos
Autores principales: Jaramillo-Rangel, Gilberto, Ortega-Martínez, Marta, Sepúlveda-Saavedra, Julio, Saucedo-Cárdenas, Odila, Montes-de-Oca-Luna, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857160/
https://www.ncbi.nlm.nih.gov/pubmed/24339722