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The α and Δ Isoforms of CREB1 Are Required to Maintain Normal Pulmonary Vascular Resistance
Chronic hypoxia causes pulmonary hypertension associated with structural alterations in pulmonary vessels and sustained vasoconstriction. The transcriptional mechanisms responsible for these distinctive changes are unclear. We have previously reported that CREB1 is activated in the lung in response...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857174/ https://www.ncbi.nlm.nih.gov/pubmed/24349008 http://dx.doi.org/10.1371/journal.pone.0080637 |