Nifedipine Treatment Reduces Resting Calcium Concentration, Oxidative and Apoptotic Gene Expression, and Improves Muscle Function in Dystrophic mdx Mice

Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans and in mdx mice by a severe and progressive destruction of muscle fibers, inflammation, oxidative/nitrosative stress, and cell death. In mdx...

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Detalles Bibliográficos
Autores principales: Altamirano, Francisco, Valladares, Denisse, Henríquez-Olguín, Carlos, Casas, Mariana, López, Jose R., Allen, Paul D., Jaimovich, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857175/
https://www.ncbi.nlm.nih.gov/pubmed/24349043
http://dx.doi.org/10.1371/journal.pone.0081222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857175/
https://www.ncbi.nlm.nih.gov/pubmed/24349043
http://dx.doi.org/10.1371/journal.pone.0081222

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