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Cartilage-Specific Overexpression of ERRγ Results in Chondrodysplasia and Reduced Chondrocyte Proliferation

While the role of estrogen receptor-related receptor alpha (ERRα) in chondrogenesis has been investigated, the involvement of ERR gamma (ERRγ) has not been determined. To assess the effect of increased ERRγ activity on cartilage development in vivo, we generated two transgenic (Tg) lines overexpress...

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Detalles Bibliográficos
Autores principales: Cardelli, Marco, Zirngibl, Ralph A., Boetto, Jonathan F., McKenzie, Kristen P., Troy, Tammy-Claire, Turksen, Kursad, Aubin, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857204/
https://www.ncbi.nlm.nih.gov/pubmed/24349082
http://dx.doi.org/10.1371/journal.pone.0081511