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Cartilage-Specific Overexpression of ERRγ Results in Chondrodysplasia and Reduced Chondrocyte Proliferation
While the role of estrogen receptor-related receptor alpha (ERRα) in chondrogenesis has been investigated, the involvement of ERR gamma (ERRγ) has not been determined. To assess the effect of increased ERRγ activity on cartilage development in vivo, we generated two transgenic (Tg) lines overexpress...
Autores principales: | Cardelli, Marco, Zirngibl, Ralph A., Boetto, Jonathan F., McKenzie, Kristen P., Troy, Tammy-Claire, Turksen, Kursad, Aubin, Jane E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857204/ https://www.ncbi.nlm.nih.gov/pubmed/24349082 http://dx.doi.org/10.1371/journal.pone.0081511 |
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