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Molecular Evidence for a Thymus-Independent Partial T Cell Development in a FOXN1(−/−) Athymic Human Fetus
The thymus is the primary organ able to support T cell ontogeny, abrogated in FOXN1(−/−) human athymia. Although evidence indicates that in animal models T lymphocytes may differentiate at extrathymic sites, whether this process is really thymus-independent has still to be clarified. In an athymic F...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857207/ https://www.ncbi.nlm.nih.gov/pubmed/24349129 http://dx.doi.org/10.1371/journal.pone.0081786 |