Molecular Evidence for a Thymus-Independent Partial T Cell Development in a FOXN1(−/−) Athymic Human Fetus

The thymus is the primary organ able to support T cell ontogeny, abrogated in FOXN1(−/−) human athymia. Although evidence indicates that in animal models T lymphocytes may differentiate at extrathymic sites, whether this process is really thymus-independent has still to be clarified. In an athymic F...

Descripción completa

Detalles Bibliográficos
Autores principales: Fusco, Anna, Panico, Luigi, Gorrese, Marisa, Bianchino, Gabriella, Barone, Maria V., Grieco, Vitina, Vitiello, Laura, D’Assante, Roberta, Romano, Rosa, Palamaro, Loredana, Scalia, Giulia, Vecchio, Luigi Del, Pignata, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857207/
https://www.ncbi.nlm.nih.gov/pubmed/24349129
http://dx.doi.org/10.1371/journal.pone.0081786

Ejemplares similares

Ejemplares similares