An Internal Ribosome Entry Site (IRES) Mutant Library for Tuning Expression Level of Multiple Genes in Mammalian Cells

A set of mutated Encephalomyocarditis virus (EMCV) internal ribosome entry site (IRES) elements with varying strengths is generated by mutating the translation initiation codons of 10(th), 11(th), and 12(th) AUG to non-AUG triplets. They are able to control the relative expression of multiple genes...

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Detalles Bibliográficos
Autores principales: Koh, Esther Y. C., Ho, Steven C. L., Mariati, Song, Zhiwei, Bi, Xuezhi, Bardor, Muriel, Yang, Yuansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857217/
https://www.ncbi.nlm.nih.gov/pubmed/24349195
http://dx.doi.org/10.1371/journal.pone.0082100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857217/
https://www.ncbi.nlm.nih.gov/pubmed/24349195
http://dx.doi.org/10.1371/journal.pone.0082100

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