Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

Following the formation of oxidatively-induced DNA damage, several DNA glycosylases are required to initiate repair of the base lesions that are formed. Recently, NEIL1 and other DNA glycosylases, including OGG1 and NTH1 were identified as potential targets in combination chemotherapeutic strategies...

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Detalles Bibliográficos
Autores principales: Jacobs, Aaron C., Calkins, Marcus J., Jadhav, Ajit, Dorjsuren, Dorjbal, Maloney, David, Simeonov, Anton, Jaruga, Pawel, Dizdaroglu, Miral, McCullough, Amanda K., Lloyd, R. Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857224/
https://www.ncbi.nlm.nih.gov/pubmed/24349107
http://dx.doi.org/10.1371/journal.pone.0081667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857224/
https://www.ncbi.nlm.nih.gov/pubmed/24349107
http://dx.doi.org/10.1371/journal.pone.0081667

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