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Immobilized transferrin Fe(3)O(4)@SiO(2) nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery

Transferrin (Tf) was immobilized onto Fe(3)O(4)@SiO(2) nanoparticles with high doxorubicin (DOX) loading (TfDMP), for dual targeting of cancer, by chemically coupling both Tf and DOX with dual-function magnetic nanoparticles (DMPs) using a multi-armed crosslinker, poly-L-glutamic acid. With high tra...

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Detalles Bibliográficos
Autores principales: Ding, Wence, Guo, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857267/
https://www.ncbi.nlm.nih.gov/pubmed/24348038
http://dx.doi.org/10.2147/IJN.S51745