Inflammasome-Mediated Inhibition of Listeria monocytogenes-Stimulated Immunity Is Independent of Myelomonocytic Function

Activation of the Nlrc4 inflammasome results in the secretion of IL-1β and IL-18 through caspase-1 and induction of pyroptosis. L. monocytogenes engineered to activate Nlrc4 by expression of Legionella pneumophilia flagellin (L. monocytogenes L.p.FlaA) are less immunogenic for CD8(+) T cell response...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Cassandra R., Dustin, Michael L., Sauer, John-Demian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857309/
https://www.ncbi.nlm.nih.gov/pubmed/24349458
http://dx.doi.org/10.1371/journal.pone.0083191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857309/
https://www.ncbi.nlm.nih.gov/pubmed/24349458
http://dx.doi.org/10.1371/journal.pone.0083191

Ejemplares similares