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Propranolol Restricts the Mobility of Single EGF-Receptors on the Cell Surface before Their Internalization

The epidermal growth factor receptor is involved in morphogenesis, proliferation and cell migration. Its up-regulation during tumorigenesis makes this receptor an interesting therapeutic target. In the absence of the ligand, the inhibition of phosphatidic acid phosphohydrolase activity by propranolo...

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Detalles Bibliográficos
Autores principales: Otero, Carolina, Linke, Max, Sanchez, Paula, González, Alfonso, Schaap, Iwan A. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857351/
https://www.ncbi.nlm.nih.gov/pubmed/24349439
http://dx.doi.org/10.1371/journal.pone.0083086