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The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules

RNA localization pathways direct numerous mRNAs to distinct subcellular regions and affect many physiological processes. In one such pathway the tumor-suppressor protein adenomatous polyposis coli (APC) targets RNAs to cell protrusions, forming APC-containing ribonucleoprotein complexes (APC-RNPs)....

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Detalles Bibliográficos
Autores principales: Yasuda, Kyota, Zhang, Huaye, Loiselle, David, Haystead, Timothy, Macara, Ian G., Mili, Stavroula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857475/
https://www.ncbi.nlm.nih.gov/pubmed/24297750
http://dx.doi.org/10.1083/jcb.201306058