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Loss of centrioles causes chromosomal instability in vertebrate somatic cells

Most animal cells contain a centrosome, which comprises a pair of centrioles surrounded by an ordered pericentriolar matrix (PCM). Although the role of this organelle in organizing the mitotic spindle poles is well established, its precise contribution to cell division and cell survival remains a su...

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Detalles Bibliográficos
Autores principales: Sir, Joo-Hee, Pütz, Monika, Daly, Owen, Morrison, Ciaran G., Dunning, Mark, Kilmartin, John V., Gergely, Fanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857480/
https://www.ncbi.nlm.nih.gov/pubmed/24297747
http://dx.doi.org/10.1083/jcb.201309038