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β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications
Increasing evidence points to nuclear compartmentalization as a contributing mechanism for gene regulation, yet mechanisms for compartmentalization remain unclear. In this paper, we use autonomous targeting of bacterial artificial chromosome (BAC) transgenes to reveal cis requirements for peripheral...
Autores principales: | Bian, Qian, Khanna, Nimish, Alvikas, Jurgis, Belmont, Andrew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857487/ https://www.ncbi.nlm.nih.gov/pubmed/24297746 http://dx.doi.org/10.1083/jcb.201305027 |
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