Discovery of a metabolic alternative to the classical mevalonate pathway

Eukarya, Archaea, and some Bacteria encode all or part of the essential mevalonate (MVA) metabolic pathway clinically modulated using statins. Curiously, two components of the MVA pathway are often absent from archaeal genomes. The search for these missing elements led to the discovery of isopenteny...

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Detalles Bibliográficos
Autores principales: Dellas, Nikki, Thomas, Suzanne T, Manning, Gerard, Noel, Joseph P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857490/
https://www.ncbi.nlm.nih.gov/pubmed/24327557
http://dx.doi.org/10.7554/eLife.00672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857490/
https://www.ncbi.nlm.nih.gov/pubmed/24327557
http://dx.doi.org/10.7554/eLife.00672

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