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Maternal high-fat diet induces hyperproliferation and alters Pten/Akt signaling in prostates of offspring

Developing recommendations for prostate cancer prevention requires identification of modifiable risk factors. Maternal exposure to high-fat diet (HFD) initiates a broad array of second-generation adult disorders in murine models and humans. Here, we investigate whether maternal HFD in mice affects i...

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Detalles Bibliográficos
Autores principales: Benesh, Emily C., Humphrey, Peter A., Wang, Qiang, Moley, Kelle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857567/
https://www.ncbi.nlm.nih.gov/pubmed/24322661
http://dx.doi.org/10.1038/srep03466