Plasma amino acids imbalance in cirrhotic patients disturbs the tricarboxylic acid cycle of dendritic cell

An imbalance of plasma amino acids (AA) is observed cirrhotic patients. Here we report that the imbalance suppresses the maturation of dendritic cells (DCs) by reducing the intracellular ATP due to interference with the mitochondrial tricarboxylic acid (TCA) cycle. We used serum-free culture medium...

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Detalles Bibliográficos
Autores principales: Kakazu, Eiji, Kondo, Yasuteru, Kogure, Takayuki, Ninomiya, Masashi, Kimura, Osamu, Ueno, Yoshiyuki, Shimosegawa, Tooru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857572/
https://www.ncbi.nlm.nih.gov/pubmed/24322372
http://dx.doi.org/10.1038/srep03459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857572/
https://www.ncbi.nlm.nih.gov/pubmed/24322372
http://dx.doi.org/10.1038/srep03459

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