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Remodelling of a polypyrimidine tract-binding protein complex during apoptosis activates cellular IRESs

Post-transcriptional control of gene expression is mediated by the interaction of RNA-binding proteins with their cognate mRNAs that specifically regulate their stability, localization and translation. mRNA-binding proteins are multifunctional and it has been proposed therefore that a combinatorial...

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Detalles Bibliográficos
Autores principales: King, H A, Cobbold, L C, Pichon, X, Pöyry, T, Wilson, L A, Booden, H, Jukes-Jones, R, Cain, K, Lilley, K S, Bushell, M, Willis, A E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857619/
https://www.ncbi.nlm.nih.gov/pubmed/24141718
http://dx.doi.org/10.1038/cdd.2013.135