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Tmprss2 Is Essential for Influenza H1N1 Virus Pathogenesis in Mice

Annual influenza epidemics and occasional pandemics pose a severe threat to human health. Host cell factors required for viral spread but not for cellular survival are attractive targets for novel approaches to antiviral intervention. The cleavage activation of the influenza virus hemagglutinin (HA)...

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Detalles Bibliográficos
Autores principales: Hatesuer, Bastian, Bertram, Stephanie, Mehnert, Nora, Bahgat, Mahmoud M., Nelson, Peter S., Pöhlman, Stefan, Schughart, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857797/
https://www.ncbi.nlm.nih.gov/pubmed/24348248
http://dx.doi.org/10.1371/journal.ppat.1003774