Structural Characterization of a Therapeutic Anti-Methamphetamine Antibody Fragment: Oligomerization and Binding of Active Metabolites

Vaccines and monoclonal antibodies (mAb) for treatment of (+)-methamphetamine (METH) abuse are in late stage preclinical and early clinical trial phases, respectively. These immunotherapies work as pharmacokinetic antagonists, sequestering METH and its metabolites away from sites of action in the br...

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Detalles Bibliográficos
Autores principales: Peterson, Eric C., Celikel, Reha, Gokulan, Kuppan, Varughese, Kottayil I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857803/
https://www.ncbi.nlm.nih.gov/pubmed/24349338
http://dx.doi.org/10.1371/journal.pone.0082690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857803/
https://www.ncbi.nlm.nih.gov/pubmed/24349338
http://dx.doi.org/10.1371/journal.pone.0082690

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