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TALE-PvuII Fusion Proteins – Novel Tools for Gene Targeting

Zinc finger nucleases (ZFNs) consist of zinc fingers as DNA-binding module and the non-specific DNA-cleavage domain of the restriction endonuclease FokI as DNA-cleavage module. This architecture is also used by TALE nucleases (TALENs), in which the DNA-binding modules of the ZFNs have been replaced...

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Detalles Bibliográficos
Autores principales: Yanik, Mert, Alzubi, Jamal, Lahaye, Thomas, Cathomen, Toni, Pingoud, Alfred, Wende, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857828/
https://www.ncbi.nlm.nih.gov/pubmed/24349308
http://dx.doi.org/10.1371/journal.pone.0082539