The Type-Specific Neutralizing Antibody Response Elicited by a Dengue Vaccine Candidate Is Focused on Two Amino Acids of the Envelope Protein

Dengue viruses are mosquito-borne flaviviruses that circulate in nature as four distinct serotypes (DENV1-4). These emerging pathogens are responsible for more than 100 million human infections annually. Severe clinical manifestations of disease are predominantly associated with a secondary infectio...

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Detalles Bibliográficos
Autores principales: VanBlargan, Laura A., Mukherjee, Swati, Dowd, Kimberly A., Durbin, Anna P., Whitehead, Stephen S., Pierson, Theodore C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857832/
https://www.ncbi.nlm.nih.gov/pubmed/24348242
http://dx.doi.org/10.1371/journal.ppat.1003761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857832/
https://www.ncbi.nlm.nih.gov/pubmed/24348242
http://dx.doi.org/10.1371/journal.ppat.1003761

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