Attenuation of Eph Receptor Kinase Activation in Cancer Cells by Coexpressed Ephrin Ligands

The Eph receptor tyrosine kinases mediate juxtacrine signals by interacting “in trans” with ligands anchored to the surface of neighboring cells via a GPI-anchor (ephrin-As) or a transmembrane segment (ephrin-Bs), which leads to receptor clustering and increased kinase activity. Additionally, solubl...

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Detalles Bibliográficos
Autores principales: Falivelli, Giulia, Lisabeth, Erika Mathes, de la Torre, Elena Rubio, Perez-Tenorio, Gizeh, Tosato, Giovanna, Salvucci, Ombretta, Pasquale, Elena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857839/
https://www.ncbi.nlm.nih.gov/pubmed/24348920
http://dx.doi.org/10.1371/journal.pone.0081445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857839/
https://www.ncbi.nlm.nih.gov/pubmed/24348920
http://dx.doi.org/10.1371/journal.pone.0081445

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