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Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonists

Since the discovery of the endomorphins (EM), the postulated endogenous peptide agonists of the mu-opioid receptors, several analogues have been synthesized to improve their binding and pharmacological profiles. We have shown previously that a new analogue, cis-1S,2R-aminocyclohexanecarboxylic acid(...

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Detalles Bibliográficos
Autores principales: Murányi, Marianna, Cinar, Resat, Kékesi, Orsolya, Birkás, Erika, Fábián, Gabriella, Bozó, Beáta, Zentai, András, Tóth, Géza, Kicsi, Emese Gabriella, Mácsai, Mónika, Dochnal, Roberta, Szabó, Gyula, Szücs, Mária
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857906/
https://www.ncbi.nlm.nih.gov/pubmed/24350273
http://dx.doi.org/10.1155/2013/501086