SYN2 is an autism predisposing gene: loss-of-function mutations alter synaptic vesicle cycling and axon outgrowth

An increasing number of genes predisposing to autism spectrum disorders (ASDs) has been identified, many of which are implicated in synaptic function. This ‘synaptic autism pathway’ notably includes disruption of SYN1 that is associated with epilepsy, autism and abnormal behavior in both human and m...

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Detalles Bibliográficos
Autores principales: Corradi, Anna, Fadda, Manuela, Piton, Amélie, Patry, Lysanne, Marte, Antonella, Rossi, Pia, Cadieux-Dion, Maxime, Gauthier, Julie, Lapointe, Line, Mottron, Laurent, Valtorta, Flavia, Rouleau, Guy A., Fassio, Anna, Benfenati, Fabio, Cossette, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857945/
https://www.ncbi.nlm.nih.gov/pubmed/23956174
http://dx.doi.org/10.1093/hmg/ddt401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857945/
https://www.ncbi.nlm.nih.gov/pubmed/23956174
http://dx.doi.org/10.1093/hmg/ddt401

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