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Identification of Unstable Network Modules Reveals Disease Modules Associated with the Progression of Alzheimer’s Disease

Alzheimer’s disease (AD), the most common cause of dementia, is associated with aging, and it leads to neuron death. Deposits of amyloid β and aberrantly phosphorylated tau protein are known as pathological hallmarks of AD, but the underlying mechanisms have not yet been revealed. A high-throughput...

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Detalles Bibliográficos
Autores principales: Kikuchi, Masataka, Ogishima, Soichi, Miyamoto, Tadashi, Miyashita, Akinori, Kuwano, Ryozo, Nakaya, Jun, Tanaka, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858171/
https://www.ncbi.nlm.nih.gov/pubmed/24348898
http://dx.doi.org/10.1371/journal.pone.0076162