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Bcl-xL Silencing Induces Alterations in hsa-miR-608 Expression and Subsequent Cell Death in A549 and SK-LU1 Human Lung Adenocarcinoma Cells

Bcl-xL is an anti-apoptotic protein that is frequently found to be overexpressed in non-small cell lung cancer leading to an inhibition of apoptosis and poor prognosis. Recently, the role of miRNAs in regulating apoptosis and cell survival during tumorigenesis has become evident, with cancer cells s...

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Detalles Bibliográficos
Autores principales: Othman, Norahayu, In, Lionel L. A., Harikrishna, Jennifer A., Hasima, Noor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858247/
https://www.ncbi.nlm.nih.gov/pubmed/24339958
http://dx.doi.org/10.1371/journal.pone.0081735