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Influence of Ovarian Hormones on Cortical Spreading Depression and Its Suppression by L-kynurenine in Rat

Migraine is sexually dimorphic and associated in 20–30% of patients with an aura most likely caused by cortical spreading depression (CSD). We have previously shown that systemic L-kynurenine (L-KYN), the precursor of kynurenic acid, suppresses CSD and that this effect depends on the stage of the es...

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Detalles Bibliográficos
Autores principales: Chauvel, Virginie, Schoenen, Jean, Multon, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858280/
https://www.ncbi.nlm.nih.gov/pubmed/24340013
http://dx.doi.org/10.1371/journal.pone.0082279