New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping

NHERF1 is a PDZ adaptor protein that scaffolds the assembly of diverse signaling complexes and has been implicated in many cancers. However, little is known about the mechanism responsible for its scaffolding promiscuity or its ability to bind to multiple targets. Computational studies have indicate...

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Detalles Bibliográficos
Autores principales: Jiang, Yuanyuan, Lu, Guorong, Trescott, Laura R., Hou, Yuning, Guan, Xiaoqing, Wang, Shuo, Stamenkovich, Angelique, Brunzelle, Joseph, Sirinupong, Nualpun, Li, Chunying, Yang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858284/
https://www.ncbi.nlm.nih.gov/pubmed/24339979
http://dx.doi.org/10.1371/journal.pone.0081904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858284/
https://www.ncbi.nlm.nih.gov/pubmed/24339979
http://dx.doi.org/10.1371/journal.pone.0081904

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