Cargando…
New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping
NHERF1 is a PDZ adaptor protein that scaffolds the assembly of diverse signaling complexes and has been implicated in many cancers. However, little is known about the mechanism responsible for its scaffolding promiscuity or its ability to bind to multiple targets. Computational studies have indicate...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858284/ https://www.ncbi.nlm.nih.gov/pubmed/24339979 http://dx.doi.org/10.1371/journal.pone.0081904 |