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Differential Responses of Neuronal and Spermatogenic Cells to the Doppel Cytotoxicity
Although structurally and biochemically similar to the cellular prion (PrP(C)), doppel (Dpl) is unique in its biological functions. There are no reports about any neurodegenerative diseases induced by Dpl. However the artificial expression of Dpl in the PrP-deficient mouse brain causes ataxia with P...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858285/ https://www.ncbi.nlm.nih.gov/pubmed/24339999 http://dx.doi.org/10.1371/journal.pone.0082130 |