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Differential Responses of Neuronal and Spermatogenic Cells to the Doppel Cytotoxicity

Although structurally and biochemically similar to the cellular prion (PrP(C)), doppel (Dpl) is unique in its biological functions. There are no reports about any neurodegenerative diseases induced by Dpl. However the artificial expression of Dpl in the PrP-deficient mouse brain causes ataxia with P...

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Detalles Bibliográficos
Autores principales: Qin, Kefeng, Ding, Tianbing, Xiao, Yi, Ma, Wenyu, Wang, Zhen, Gao, Jimin, Zhao, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858285/
https://www.ncbi.nlm.nih.gov/pubmed/24339999
http://dx.doi.org/10.1371/journal.pone.0082130