Klotho Suppresses Cardiomyocyte Apoptosis in Mice with Stress-Induced Cardiac Injury via Downregulation of Endoplasmic Reticulum Stress

Cardiomyocyte apoptosis is a common pathological alteration in heart disease which results in systolic dysfunction or sudden death. Klotho is a novel anti-aging hormone. We tested the effects of klotho on cell apoptosis in isoproterenol-treated cardiomyocytes. In BALB/c mice, cardiac injury was indu...

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Detalles Bibliográficos
Autores principales: Song, Shuang, Gao, Pan, Xiao, Hang, Xu, Yan, Si, Lian Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858310/
https://www.ncbi.nlm.nih.gov/pubmed/24340070
http://dx.doi.org/10.1371/journal.pone.0082968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858310/
https://www.ncbi.nlm.nih.gov/pubmed/24340070
http://dx.doi.org/10.1371/journal.pone.0082968

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