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Natural Killer Cell-Dependent Anti-Fibrotic Pathway in Liver Injury via Toll-Like Receptor-9

The toll-like receptor-9 (TLR9) agonist cytosine phosphate guanine (CpG), activates hepatic stellate cells (HSCs) and mediates fibrosis. We investigated the TLR9 effects on lymphocyte/HSCs interactions. Liver fibrosis was induced in wild-type (WT) mice by intra-peritoneal carbon-tetrachloride (CCl(4...

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Detalles Bibliográficos
Autores principales: Abu-Tair, Lina, Axelrod, Jonathan H., Doron, Sarit, Ovadya, Yossi, Krizhanovsky, Valery, Galun, Eithan, Amer, Johnny, Safadi, Rifaat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858328/
https://www.ncbi.nlm.nih.gov/pubmed/24340043
http://dx.doi.org/10.1371/journal.pone.0082571