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UV-Photoconversion of Ethosuximide from a Longevity-Promoting Compound to a Potent Toxin
The anticonvulsant ethosuximide has been previously shown to increase life span and promote healthspan in the nematode Caenorhabditis elegans at millimolar concentrations. Here we report that following exposure to ultraviolet irradiation at 254 nm, ethosuximide is converted into a compound that disp...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858337/ https://www.ncbi.nlm.nih.gov/pubmed/24340038 http://dx.doi.org/10.1371/journal.pone.0082543 |