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Utilizing Twins as Controls for Non-Twin Case-Materials in Genome Wide Association Studies

Twin registries around the globe have collected DNA samples from large numbers of monozygotic and dizygotic twins. The twin sample collections are frequently used as controls in disease-specific studies together with non-twins. This approach is unbiased under the hypothesis that twins and singletons...

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Detalles Bibliográficos
Autores principales: Ganna, Andrea, Ortega-Alonso, Alfredo, Havulinna, Aki, Salomaa, Veikko, Kaprio, Jaakko, Pedersen, Nancy L., Sullivan, Patrick F., Ingelsson, Erik, Hultman, Christina M., Magnusson, Patrik K. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858365/
https://www.ncbi.nlm.nih.gov/pubmed/24340086
http://dx.doi.org/10.1371/journal.pone.0083101