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Utilizing Twins as Controls for Non-Twin Case-Materials in Genome Wide Association Studies
Twin registries around the globe have collected DNA samples from large numbers of monozygotic and dizygotic twins. The twin sample collections are frequently used as controls in disease-specific studies together with non-twins. This approach is unbiased under the hypothesis that twins and singletons...
Autores principales: | Ganna, Andrea, Ortega-Alonso, Alfredo, Havulinna, Aki, Salomaa, Veikko, Kaprio, Jaakko, Pedersen, Nancy L., Sullivan, Patrick F., Ingelsson, Erik, Hultman, Christina M., Magnusson, Patrik K. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858365/ https://www.ncbi.nlm.nih.gov/pubmed/24340086 http://dx.doi.org/10.1371/journal.pone.0083101 |
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