Mechanisms of Rapid Reactive Oxygen Species Generation in Response to Cytosolic Ca(2+) or Zn(2+) Loads in Cortical Neurons

Excessive “excitotoxic” accumulation of Ca(2+) and Zn(2+) within neurons contributes to neurodegeneration in pathological conditions including ischemia. Putative early targets of these ions, both of which are linked to increased reactive oxygen species (ROS) generation, are mitochondria and the cyto...

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Detalles Bibliográficos
Autores principales: Clausen, Aaron, McClanahan, Taylor, Ji, Sung G., Weiss, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858366/
https://www.ncbi.nlm.nih.gov/pubmed/24340096
http://dx.doi.org/10.1371/journal.pone.0083347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858366/
https://www.ncbi.nlm.nih.gov/pubmed/24340096
http://dx.doi.org/10.1371/journal.pone.0083347

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