Cell Cycle-Dependent Turnover of 5-Hydroxymethyl Cytosine in Mouse Embryonic Stem Cells

Hydroxymethylcytosine in the genome is reported to be an intermediate of demethylation. In the present study, we demonstrated that maintenance methyltransferase Dnmt1 scarcely catalyzed hemi-hydroxymethylated DNA and that the hemi-hydroxymethylated DNA was not selectively recognized by the SRA domai...

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Detalles Bibliográficos
Autores principales: Otani, Junji, Kimura, Hironobu, Sharif, Jafar, Endo, Takaho A., Mishima, Yuichi, Kawakami, Toru, Koseki, Haruhiko, Shirakawa, Masahiro, Suetake, Isao, Tajima, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858372/
https://www.ncbi.nlm.nih.gov/pubmed/24340069
http://dx.doi.org/10.1371/journal.pone.0082961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858372/
https://www.ncbi.nlm.nih.gov/pubmed/24340069
http://dx.doi.org/10.1371/journal.pone.0082961

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