Identification of novel small molecule inhibitors of centrosome clustering in cancer cells

Most normal cells have two centrosomes that form bipolar spindles during mitosis, while cancer cells often contain more than two, or “supernumerary” centrosomes. Such cancer cells achieve bipolar division by clustering their centrosomes into two functional poles, and inhibiting this process then lea...

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Detalles Bibliográficos
Autores principales: Kawamura, Eiko, Fielding, Andrew B., Kannan, Nagarajan, Balgi, Aruna, Eaves, Connie J., Roberge, Michel, Dedhar, Shoukat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858562/
https://www.ncbi.nlm.nih.gov/pubmed/24091544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858562/
https://www.ncbi.nlm.nih.gov/pubmed/24091544

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