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Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector

Autophagy plays an important role in neoplastic transformation of cells and in resistance of cancer cells to radio- and chemotherapy. p62 (SQSTM1) is a key component of autophagic machinery which is also involved in signal transduction. Although recent empirical observations demonstrated that p62 is...

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Detalles Bibliográficos
Autores principales: Venanzi, Franco, Shifrin, Victor, Sherman, Michael Y., Gabai, Vladimir, Kiselev, Oleg, Komissarov, Andrey, Grudinin, Mikhail, Shartukova, Maria, Romanovskaya-Romanko, Ekaterina A., Kudryavets, Yuri, Bezdenezhnykh, Natalya, Lykhova, Oleksandra, Semesyuk, Nadiia, Concetti, Antonio, Tsyb, Anatoly, Filimonova, Marina, Makarchuk, Victoria, Yakubovsky, Raisa, Chursov, Andrey, Shcherbinina, Vita, Shneider, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858567/
https://www.ncbi.nlm.nih.gov/pubmed/24121124