Ginsenoside Rd promotes glutamate clearance by up-regulating glial glutamate transporter GLT-1 via PI3K/AKT and ERK1/2 pathways

Ginsenoside Rd (Rd), one of the main active ingredients in Panax ginseng, has been showed to protect against ischemic cerebral damage both in vitro and in vivo. However, the underlying mechanism of Rd is largely unknown. Excessive extracellular glutamate causes excitatory toxicity, leading to cell d...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Shi, Ming, Bjørås, Magnar, Wang, Wei, Zhang, Guangyun, Han, Junliang, Liu, Zhirong, Zhang, Yunxia, Wang, Bing, Chen, Jing, Zhu, Yi, Xiong, Lize, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858668/
https://www.ncbi.nlm.nih.gov/pubmed/24376419
http://dx.doi.org/10.3389/fphar.2013.00152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858668/
https://www.ncbi.nlm.nih.gov/pubmed/24376419
http://dx.doi.org/10.3389/fphar.2013.00152

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