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Vibrio campbellii hmgA-mediated pyomelanization impairs quorum sensing, virulence, and cellular fitness

Melanization due to the inactivation of the homogentisate-1,2-dioxygenase gene (hmgA) has been demonstrated to increase stress resistance, persistence, and virulence in some bacterial species but such pigmented mutants have not been observed in pathogenic members of the Vibrio Harveyi clade. In this...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Lin, Baochuan, Mostaghim, Anahita, Rubin, Robert A., Glaser, Evan R., Mittraparp-arthorn, Pimonsri, Thompson, Janelle R., Vuddhakul, Varaporn, Vora, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858670/
https://www.ncbi.nlm.nih.gov/pubmed/24376440
http://dx.doi.org/10.3389/fmicb.2013.00379