Retrograde Endocannabinoid Signaling Reduces GABAergic Synaptic Transmission to Gonadotropin-Releasing Hormone Neurons

Cannabinoids suppress fertility via reducing hypothalamic GnRH output. γ-Aminobutyric acid (GABA)(A) receptor (GABA(A)-R)-mediated transmission is a major input to GnRH cells that can be excitatory. We hypothesized that cannabinoids act via inhibiting GABAergic input. We performed loose-patch electr...

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Detalles Bibliográficos
Autores principales: Farkas, Imre, Kalló, Imre, Deli, Levente, Vida, Barbara, Hrabovszky, Erik, Fekete, Csaba, Moenter, Suzanne M., Watanabe, Masahiko, Liposits, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Endocrine Society 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858799/
https://www.ncbi.nlm.nih.gov/pubmed/20926585
http://dx.doi.org/10.1210/en.2010-0638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858799/
https://www.ncbi.nlm.nih.gov/pubmed/20926585
http://dx.doi.org/10.1210/en.2010-0638

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