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Interferon regulatory factor-8 modulates the development of tumour-induced CD11b(+)Gr-1(+) myeloid cells
Tumour-induced myeloid-derived suppressor cells (MDSC) promote immune suppression and mediate tumour progression. However, the molecular basis for the generation of MDSC, which in mice co-express the CD11b(+) and Gr-1(+) cell surface markers remains unclear. Because CD11b(+)Gr-1(+) cells expand duri...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858838/ https://www.ncbi.nlm.nih.gov/pubmed/20196788 http://dx.doi.org/10.1111/j.1582-4934.2009.00685.x |