Interferon regulatory factor-8 modulates the development of tumour-induced CD11b(+)Gr-1(+) myeloid cells

Tumour-induced myeloid-derived suppressor cells (MDSC) promote immune suppression and mediate tumour progression. However, the molecular basis for the generation of MDSC, which in mice co-express the CD11b(+) and Gr-1(+) cell surface markers remains unclear. Because CD11b(+)Gr-1(+) cells expand duri...

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Detalles Bibliográficos
Autores principales: Stewart, Trina J, Greeneltch, Kristy M, Reid, Julia E, Liewehr, David J, Steinberg, Seth M, Liu, Kebin, Abrams, Scott I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Molecular Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858838/
https://www.ncbi.nlm.nih.gov/pubmed/20196788
http://dx.doi.org/10.1111/j.1582-4934.2009.00685.x

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